|
|
Company: |
Chemical Genomics Core |
|
Headquarters: |
Indiana University School of Medicine, 635 Brnhill D.
Indianapolis,
IN
46202 |
|
Web Site Address: |
www.chemicalgenomics.iu.edu |
|
Number of Employees: |
4 |
|
Company Description: |
|
The Chemical Genomics Core Facility (CGCF) at the Indiana University School of Medicine (IUSM) was established in the summer of 2005 at the Department of Biochemistry and Molecular Biology. It is located at the Medical Science building of the IU Medical Center. CGCF is directed by Dr. Zhong-Yin Zhang, the chairman of the Department of Biochemistry and Molecular Biology. The core provides cost-effective access to high throughput screening (HTS) of structurally-diverse, drug-like small molecules in biological assays provided by the investigators. This would enable the investigators to discover small molecule tools for basic research, therapeutic development and diagnostic applications. The core facility incorporates state-of-art automated instrumentation, a total collection of 160,000 small molecule compound library, computer database, and a staff experienced in assay development, high throughput screening and laboratory robotics. The core facility is a service and collaborative research resource where facility staff works closely with each investigator through all stages of the screening process. In the near future, the chemical genomics core facility will further develop its medicinal chemistry capabilities for targeted chemical synthesis, which will be dedicated to the optimization of lead compounds discovered from the HTS in order to enhance therapeutic properties of the lead compounds, including potency and selectivity, as well as bioavailability and toxicity. |
|
Services provided by category: |
|
Assay Development, Chemistry, High-throughput screening, Lead Discovery, Screening |
|
|
|
|
