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Company Description: |
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Given the increased demand for customized chemical syntheses of drug leads and biological probes on the IUPUI campus, the Department of Chemistry & Chemical Biology of the School of Science has joined forces with the IU Simon Cancer Center (IUSCC) to create a core facility for Chemical Synthesis & Organic Drug Lead Development to expedite the translational research and drug development efforts of cancer researchers and others.
The goal of the Synthesis Core is to support the synthetic and medicinal chemistry needs of IUSCC investigators as well as other academic entities within IUPUI and throughout the state; the core is also available to the broader life sciences industrial community of central Indiana and elsewhere on a contract basis. The core is directed by Dr. Eric C. Long, Professor & Associate Chair of the Department of Chemistry & Chemical Biology within the School of Science while the core is managed by the Director of Synthesis, Dr. Tax Georgiadis. Dr. Georgiadis is a synthetic/medicinal chemist with greater than 20 years of experience in both industrial and academic settings.
The services currently offered by the core include: Custom Syntheses of Investigator-Requested Compounds including literature-cited compounds, patented agents, compounds discovered through high-throughput screening, experimental agents, and focused libraries and Medicinal Chemistry Support such as assistance in achieving improved ADMET (adsorption, distribution, metabolism, excretion, toxicity) properties of lead compounds to improve biological activity, lead optimization (SAR analysis), database searching and data mining of drug discovery targets, insight on the patentability of chemical matter, and chemical informatics.
http://www.chem.iupui.edu/Facilities/core/index.php |
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Services provided by category: |
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ADMET, Analytical Chemistry, Chemical Analysis, Chemistry, Chemoinformatics, Combinatorial Chemistry, Compound Generation, Consulting, Compound Synthesis, Discovery, Drug Design, Drug Discovery Services, High-speed Analogue Synthesis, Lead Discovery, Lead Optimization, Medicinal Chemistry, SAR Evaluation, Scale-Up Synthesis, Target Identification |
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